Wayne Rooney is expected to return to the starting line-up after recovering from a virus. Man United will still be without Rio Ferdinand, Anderson and Owen Hargreaves.
Man United squad: Van der Sar, Kuszczak, Neville, Rafael, O'Shea, Vidic, Evans, Brown, Smalling, Evra, Fabio, Valencia, Gibson, Fletcher, Carrick, Scholes, Giggs, Nani, Rooney, Berbatov, Hernandez, Owen and Macheda.
Jack Collison, Peter Kurucz, Zavon Hines and Thomas Hitzlsperger are all out injured for the Hammers. Carlton Cole, Rob and Kieron Dyer should return, after sitting out the midweek League Cup win over Oxford.
West Ham squad: Green, Stech, Upson, Tomkins, Ilunga, Ben Haim, Gabbidon, Spector, Da Costa, Reid, Daprela, Noble, Parker, Kovac, Barrera, Faubert, Boa Morte, Dyer, McCarthy, Sears, Nouble, Stanislas, Piquionne, Cole, McCarthy and Obinna
The referee tomorrow is Mark Clattenburg, he took charge of Chelsea's 6-0 win over West Brom at Stamford Bridge. Last season he refereed 42 games, showing 105 yellow cards and five red cards.
Last season Clattenburg refereed four matches involving Manchester United. They were the 2-1 win over Bolton at Old Trafford, 1-1 draw away to Birmingham, the 4-0 home win over Stoke and the 2-0 win over Spurs in the League Cup.
