Tonight Manchester United and Arsenal go head to head for the first time in Europe and it doesn't really get much bigger (apart from the final).
Manchester United will be without defender and captain Gary Neville and long time absentee Owen Hargreaves but that is it. John O'Shea has recovered from an injury and Wes Brown is back after injury but is not ready to start so he will probably be on the bench.
Arsenal have former Man United player Mikael Silvestre in the squad and has be declared as fit for tonight's game. Kieran Gibbs who was expected to play a big role in marking Cristiano Ronaldo is also a doubt with an ankle injury.
Arsenal are without Gael Clichy and Robin van Persie who are both out injured although Clichy should be fit for the second leg next Tuesday and Andrey Arshavin is not eligible to play.
If Patrice Evra (Man United) and Wayne Rooney (Man United), Abou Diaby (Arsenal), Alexandre Song (Arsenal) and Samir Nasri (Arsenal) are booked then they will miss the second leg at the Emirates.
Fergie's main problem is deciding what attacking players to pick and what selection he has to choose from- Cristiano Ronaldo, Carlos Tevez, Wayne Rooney and Dimitar Berbatov. Patrice Evra will have a difficult job trying to keep Theo Walcott under control but I believe that he is capable of doing it but saying that he did struggle against Tottenham's Aaron Lennon earlier on in the season.
As long as Man United score and keep a clean sheet then I will be happy, we are capable of going to the Emirates and scoring so if we don't concede tonight then it will put us in a great postion.
Man United Squad: Van der Sar, Foster, Kuszczak, O'Shea, Brown, Ferdinand, Vidic, Evans, Evra, Rafael, Ronaldo, Nani, Carrick, Scholes, Fletcher, Anderson, Giggs, Park, Berbatov, Rooney, Tevez.
Arsenal Squad: Almunia, Sagna, Toure, Silvestre, Gibbs, Nasri, Song, Denilson, Fabregas, Walcott, Adebayor, Fabianski, Djourou, Eduardo, Bendtner, Diaby, Vela, Ramsey, Eboue.
Arsenal Squad: Almunia, Sagna, Toure, Silvestre, Gibbs, Nasri, Song, Denilson, Fabregas, Walcott, Adebayor, Fabianski, Djourou, Eduardo, Bendtner, Diaby, Vela, Ramsey, Eboue.